Perfection by possession will usually mean the secured party taking physical possession of the collateral. In most cases, this will only be practical for small and valuable items, and where the grantor does not require the day to day possession of collateral to use in any business or operations.
An alternative to the secured party taking physical possession themselves is available only for goods, and involves taking possession through another person as agent or bailee1.
A secured party could conceivably take possession through a bailee either
The bailee through whom a secured party possesses collateral cannot for obvious reasons be the grantor or the debtor2.
Taking possession of collateral through a bailee is a form of constructive possession, but as noted above, is only available for goods.